We went too slow and only saw the Origen Museum and the Nevada State Museum. We'll have to go back next year! The Origen Museum covers human history of the Springs Preserve and Las Vegas which includes Native Americans, land auctions, the growth of the railroad, Hoover Dam, and a simulated flash flood. The Nevada State Museum features fossils, early settlers, the beginnings of Las Vegas and Reno, and a changing exhibit gallery.
The museums are accessible but a long, paved uphill path must be navigated to get to the entrances. One exhibit in the Origen Museum is too high to view. We walked/rolled part of the way along the accessible, paved Exploration Loop Trail but didn't have enough time to go from the trail access point at the tram station to Boomtown, approximately 1/3 mile. The entire loop is 3.5 miles. The tram (trackless train) is accessible and I think it goes around the entire loop with a stop at Boomtown.